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The manufacture of a novel 3D hydroxyapatite microstructure derived from cuttlefish bones for potential tissue engineering applications
Journal article   Open access   Peer reviewed

The manufacture of a novel 3D hydroxyapatite microstructure derived from cuttlefish bones for potential tissue engineering applications

G.E.J. Poinern and D. Fawcett
American Journal of Materials Science, Vol.3(5), pp.13-135
2013
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Abstract

Porous three-dimensional hydroxyapatite scaffolds were synthesised from aragonitic cuttlefish bones via a microwave based technique. Due to its close similarity to the mineral phase found in the natural human bone matrix, synthetically produced hydroxyapatite is considered a viable apatite substitute for natural bone in a number of biomedical applications. The X-ray diffraction data confirms the conversion of crystalline formations of calcium carbonate, the main component of the cuttlefish, to hydroxyapatite. The synthesis process is straightforward, efficient and creates a highly porous 3 dimensional microstructure that has the potential to be used in a wide range of hard tissue engineering applications such as bone repair, filling material and bone augmentation.

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