Journal article
The mouse as a model for the effects of MHC genes on human disease
Immunology Today, Vol.21(7), pp.328-332
2000
Abstract
As mice are often used to model human major histocompatibility complex (MHC)-associated diseases, it is important to understand how their MHC regions differ at the DNA level. The sequencing of the mouse MHC (H2 region) has enabled a detailed map of this region to be assembled for comparison with the human MHC. Here, Richard Allcock and colleagues outline the similarities between the human and mouse MHC regions and discuss notable differences that might affect disease models.
Details
- Title
- The mouse as a model for the effects of MHC genes on human disease
- Authors/Creators
- R.J.N. Allcock (Author/Creator)A.M. Martin (Author/Creator)P. Price (Author/Creator)
- Publication Details
- Immunology Today, Vol.21(7), pp.328-332
- Publisher
- Elsevier BV
- Identifiers
- 991005541261107891
- Copyright
- © Elsevier B.V.
- Murdoch Affiliation
- Institute for Immunology and Infectious Diseases
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.6 Immunology
- 1.6.607 MHC Diversity
- Web Of Science research areas
- Immunology
- ESI research areas
- Immunology