The seroprevalence and distribution of Toxoplasma gondii in pigs in China from 2000 to 2023: a systematic review and meta-analysis

Ping Liu; Hao Tang; Quangang Xu; Yaqin Dong; Feng Chen; Dazhuo Zhao; Bin Tang; Xiangdong Sun; Xiaolei Liu; Mingyuan Liu; Youming Wang

doi:10.1186/s44149-025-00173-y

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The seroprevalence and distribution of Toxoplasma gondii in pigs in China from 2000 to 2023: a systematic review and meta-analysis

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The seroprevalence and distribution of Toxoplasma gondii in pigs in China from 2000 to 2023: a systematic review and meta-analysis

Ping Liu, Hao Tang, Quangang Xu, Yaqin Dong, Feng Chen, Dazhuo Zhao, Bin Tang, Xiangdong Sun, Xiaolei Liu, Mingyuan Liu, …

Animal diseases, Vol.5(1), 26

2025

DOI: https://doi.org/10.1186/s44149-025-00173-y

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Abstract

Life Sciences & Biomedicine

Science & Technology

Veterinary Sciences

Toxoplasma gondii (T. gondii) is a globally distributed parasite that can infect a diversity of warm-blooded animals, including swine and humans. Infection in swine poses a considerable threat to food safety and public health. The aim of this meta-analysis was to estimate the seroprevalence of T. gondii infection in the swine population in China from 2000 to 2023 and to examine potential factors associated with infection. A total of 112 studies were included, collectively involving 145,152 swine samples originating from 26 provinces. The pooled seroprevalence was 26.0% (95% CI: 23.3%-28.7%). Stratified analysis based on diagnostic methods revealed that studies using the indirect hemagglutination assay (IHA) reported a seroprevalence of 19.7% (95% CI: 17.2%-22.2%), whereas those utilizing the enzyme-linked immunosorbent assay (ELISA) reported a higher seroprevalence of 35.5% (95% CI: 29.1%-41.8%). Geographical analysis indicated higher seroprevalence in the South Central and Southwest regions, whereas the East and Northwest areas reported the lowest seroprevalence. Chongqing Province reported the highest seroprevalence, reaching 44.9% (95% CI: 43.4%-46.0%), followed by Xinjiang, Hainan, and Guizhou, whereas the lowest was observed in Shandong Province (3.5%, 95% CI: 1.7%-6.1%). These findings provide important epidemiological evidence that can inform strategies for the prevention and control of T. gondii infection in swine populations, with a focus on high-risk populations and geographical areas. This imperative contributes substantially to the improvement of both food safety and public health.

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Title: The seroprevalence and distribution of Toxoplasma gondii in pigs in China from 2000 to 2023: a systematic review and meta-analysis
Authors/Creators: Ping Liu - Jilin University
Hao Tang - Murdoch University
Quangang Xu - China Anim Hlth & Epidemiol Ctr, Qingdao 266032, Shandong, Peoples R China
Yaqin Dong - China Anim Hlth & Epidemiol Ctr, Qingdao 266032, Shandong, Peoples R China
Feng Chen - Shandong Prevent Ctr Anim Dis Control, Jinan 250100, Shandong, Peoples R China
Dazhuo Zhao - Yanbian Korean Nationality Autonomous Prefecture A, Yanji 133002, Jilin, Peoples R China
Bin Tang - Jilin University
Xiangdong Sun - China Animal Health and Epidemiology Center
Xiaolei Liu - Jilin University
Mingyuan Liu - Jilin University
Youming Wang - China Animal Health and Epidemiology Center
Publication Details: Animal diseases, Vol.5(1), 26
Publisher: Springer Nature
Number of pages: 16
Grant note: 2022YFE0114400 / Key Technologies Research and Development Program 2022YFE0114400 / National Key Research and Development Program; National Key Research & Development Program of China
Identifiers: 991005794765207891
Murdoch Affiliation: School of Veterinary Medicine
Language: English
Resource Type: Journal article

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