Journal article
The survival of PCR-amplifiable DNA in cow leather
Journal of Archaeological Science, Vol.34(5), pp.823-829
2007
Abstract
We have investigated the survival of PCR-amplifiable mitochondrial and nuclear DNA in a small number of modern and medieval bovine leather samples. The results of this preliminary investigation demonstrate that, while no nuclear DNA can be PCR-amplified from any of the specimens, mitochondrial DNA can be amplified from all samples. To investigate this contrasting pattern of DNA survival further, we have vegetable-tanned cow skin in our own laboratory, and directly assayed the survival of PCR-amplifiable mitochondrial and nuclear DNA at each step of the process. The results indicate that nuclear DNA is reduced to sub-amplifiable levels as a result of the tanning baths, whereas amplifiable mitochondrial DNA survives the complete process. Our results suggest that old and archaeological bovine leather may represent a useful source of genetic information, although this information will most likely be limited to that which can be gained from mitochondrial DNA.
Details
- Title
- The survival of PCR-amplifiable DNA in cow leather
- Authors/Creators
- A. Vuisso (Author/Creator)M. Worobey (Author/Creator)N. Odegaard (Author/Creator)M. Bunce (Author/Creator)C. A. Machado (Author/Creator)N. Lynnerup (Author/Creator)E. E. Peacock (Author/Creator)M. T. P. Gilbert (Author/Creator)
- Publication Details
- Journal of Archaeological Science, Vol.34(5), pp.823-829
- Publisher
- Elsevier
- Identifiers
- 991005541494507891
- Copyright
- © 2006 Elsevier Ltd
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.189 Genome Studies
- 1.189.310 Population Genetics
- Web Of Science research areas
- Anthropology
- Archaeology
- Geosciences, Multidisciplinary
- ESI research areas
- Social Sciences, general