Journal article
Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 1 Historical and established therapies
Journal of Clinical Neuroscience, Vol.21(11), pp.1835-1846
2014
Abstract
Multiple sclerosis (MS) is a potentially life-changing immune mediated disease of the central nervous system. Until recently, treatment has been largely confined to acute treatment of relapses, symptomatic therapies and rehabilitation. Through persistent efforts of dedicated physicians and scientists around the globe for 160 years, a number of therapies that have an impact on the long term outcome of the disease have emerged over the past 20 years. In this three part series we review the practicalities, benefits and potential hazards of each of the currently available and emerging treatment options for MS. We pay particular attention to ways of abrogating the risks of these therapies and provide advice on the most appropriate indications for using individual therapies. In Part 1 we review the history of the development of MS therapies and its connection with the underlying immunobiology of the disease. The established therapies for MS are reviewed in detail and their current availability and indications in Australia and New Zealand are summarised. We examine the evidence to support their use in the treatment of MS.
Details
- Title
- Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 1 Historical and established therapies
- Authors/Creators
- S.A. Broadley (Author/Creator) - Griffith UniversityM.H. Barnett (Author/Creator) - The University of SydneyM. Boggild (Author/Creator) - Townsville HospitalB.J. Brew (Author/Creator) - St Vincent's HealthH. Butzkueven (Author/Creator) - The Royal Melbourne HospitalR. Heard (Author/Creator) - The University of SydneyS. Hodgkinson (Author/Creator) - UNSW SydneyA.G. Kermode (Author/Creator) - The University of Western AustraliaJ. Lechner-Scott (Author/Creator) - Hunter Medical Research InstituteR.A.L. Macdonell (Author/Creator) - Austin HealthM. Marriott (Author/Creator) - The Royal Melbourne HospitalD.F. Mason (Author/Creator) - Christchurch HospitalJ. Parratt (Author/Creator) - The University of SydneyS.W. Reddel (Author/Creator) - The University of SydneyC.P. Shaw (Author/Creator) - Deakin UniversityM. Slee (Author/Creator) - Flinders Medical CentreJ. Spies (Author/Creator) - The University of SydneyB.V. Taylor (Author/Creator) - Menzies Research InstituteW.M. Carroll (Author/Creator) - The University of Western AustraliaT.J. Kilpatrick (Author/Creator) - Menzies Research InstituteJ. King (Author/Creator) - Florey Institute of Neuroscience and Mental HealthP.A. McCombe (Author/Creator) - The University of QueenslandJ.D. Pollard (Author/Creator) - The University of SydneyE. Willoughby (Author/Creator) - Auckland City Hospital
- Publication Details
- Journal of Clinical Neuroscience, Vol.21(11), pp.1835-1846
- Publisher
- Churchill Livingstone
- Identifiers
- 991005543069607891
- Copyright
- Crown Copyright © 2014.
- Murdoch Affiliation
- Institute for Immunology and Infectious Diseases
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
51 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.203 Neuromuscular Disorders
- 1.203.147 Multiple Sclerosis
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior