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Thermal and ultrasonic influence in the formation of nanometer scale hydroxyapatite bio-ceramic
Journal article   Open access   Peer reviewed

Thermal and ultrasonic influence in the formation of nanometer scale hydroxyapatite bio-ceramic

G.E.J. Poinern, R.K. Brundavanam, X.T. Le, S. Djordjevic, M. Prokic and D. Fawcett
International Journal of Nanomedicine, (6), pp.2083-2095
2011
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Abstract

Hydroxyapatite (HAP) is a widely used biocompatible ceramic in many biomedical applications and devices. Currently nanometer-scale forms of HAP are being intensely investigated due to their close similarity to the inorganic mineral component of the natural bone matrix. In this study nano-HAP was prepared via a wet precipitation method using Ca(NO3)2 and KH2PO4 as the main reactants and NH4OH as the precipitator under ultrasonic irradiation. The Ca/P ratio was set at 1.67 and the pH was maintained at 9 during the synthesis process. The influence of the thermal treatment was investigated by using two thermal treatment processes to produce ultrafine nano-HAP powders. In the first heat treatment, a conventional radiant tube furnace was used to produce nano-particles with an average size of approximately 30 nm in diameter, while the second thermal treatment used a microwave-based technique to produce particles with an average diameter of 36 nm. The crystalline structure and morphology of all nanoparticle powders produced were investigated using X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). Both thermal techniques effectively produced ultrafine powders with similar crystalline structure, morphology and particle sizes.

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Collaboration types
International collaboration
Citation topics
2 Chemistry
2.165 Nanofibers, Scaffolds & Fabrication
2.165.163 Hydroxyapatite Composites
Web Of Science research areas
Nanoscience & Nanotechnology
Pharmacology & Pharmacy
ESI research areas
Pharmacology & Toxicology
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