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Time to Hang Up the Gloves: A Scoping Review of Evidence on Non-Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration
Journal article   Open access   Peer reviewed

Time to Hang Up the Gloves: A Scoping Review of Evidence on Non-Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration

Natasya Raja Azlan, Debbie Massey, Lesley Andrew, Amanda Towell-Barnard, Seng Giap Marcus Ang, Carol Crevacore, Martina Costello, Aaron Alejandro, Weiting Liu, Naila Zaman, …
Journal of advanced nursing, Early View
2025
DOI: https://doi.org/10.1111/jan.70197
PMID: 40999763
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CC BY V4.0,  Open Access

Abstract

patient safety sustainable healthcare infection prevention and control intravenous antimicrobials evidence‐based practice hand hygiene non‐sterile glove use
Aims To systematically summarise evidence related to the use of non-sterile gloves when preparing and administering intravenous antimicrobials. Design Scoping review. Methods A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for scoping review guidelines (2018). Five databases and grey literature were included in the search. Literature published between 2009 and 2024 was included. Data Sources Five databases (Medline, CINAHL, EMBASE, Scopus and Web of Science) and the grey literature were searched in February 2024. Results Three studies were included; however, none directly addressed correct non-sterile glove use during intravenous antimicrobial preparation or administration in clinical practice. Conclusion We found no evidence to support the use of non-sterile gloves in intravenous antimicrobial preparation. There is an urgent need for rigorous research to inform the development of clear guidelines on non-sterile glove use to underpin evidence-based decision-making in nursing and other health professional education, improve patient outcomes, reduce healthcare costs and promote environmental sustainability in healthcare. Implications Inappropriate use of non-sterile gloves for preparing and administering intravenous antimicrobials hinders correct hand hygiene practices and increases healthcare-associated infections, healthcare costs and waste. Impact A critical gap in the existing evidence was a key finding of this review, highlighting the urgency for evidence-based guidelines to improve patient safety outcomes, reduce healthcare costs and promote environmental sustainability in healthcare. Reporting Method This scoping review adhered to the relevant EQUATOR guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) reporting checklist. Patient of Public Contribution This study did not include patient or public involvement in its design, conduct or reporting. Trial and Protocol Registration The protocol was registered on Open Science Framework (https://doi.org/10.17605/OSF.IO/QY4J2).

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UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

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86 File views/ downloads
16 Record Views
1 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.23 Antibiotics & Antimicrobials
1.23.173 MRSA and VRE
Web Of Science research areas
Nursing
ESI research areas
Clinical Medicine
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