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Transcranial magnetic stimulation reveals asymmetrical efficacy of intracortical circuits in primary motor cortex
Journal article   Peer reviewed

Transcranial magnetic stimulation reveals asymmetrical efficacy of intracortical circuits in primary motor cortex

G. Hammond, D. Faulkner, M. Byrnes, F. Mastaglia and G. Thickbroom
Experimental Brain Research, Vol.155(1), pp.19-23
2004
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Abstract

The efficacy of inhibitory and excitatory intracortical circuits acting on the representation of an intrinsic hand muscle in the primary motor cortex of both hemispheres was measured with paired transcranial mag- netic stimuli in right-handed subjects. Both intracortical inhibition (measured with an interstimulus interval of 3 ms) and intracortical facilitation (measured with an interstimulus interval of 16 ms) developed more rapidly with increasing conditioning stimulus intensity in the dominant than the non-dominant hand. We conclude that the intracortical circuits in the primary motor cortex are more potent in the dominant than the non-dominant hemisphere, and hypothesize that this difference is a factor in the asymmetrical dexterity associated with hand preference.

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Citation topics
1 Clinical & Life Sciences
1.82 Gait & Posture
1.82.811 Transcranial Magnetic Stimulation
Web Of Science research areas
Neurosciences
ESI research areas
Neuroscience & Behavior
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