Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection

S.K. Chaubey; A.K. Sinha; E. Phillips; D.B. Russell; H. Falhammar

doi:10.1071/SH09005

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Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection

Journal article

Open access

Peer reviewed

Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection

S.K. Chaubey, A.K. Sinha, E. Phillips, D.B. Russell and H. Falhammar

Sexual Health, Vol.6(3), pp.254-257

2009

DOI: https://doi.org/10.1071/SH09005

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Abstract

A 42-year-old Thai man was administered the combination drugs liponavir/ritonavir and abacavir/lamivudine. On day 3 he was admitted and his electrocardiogram demonstrated sinus arrest with junctional escape rhythm with a rate of 42 min-1. Three days after stopping the medication he reverted to normal sinus rhythm. A 55-year-old Caucasian man was admitted to hospital with triple vessel disease. He had a permanent pace maker inserted 4 years previously for Mobitz type II AV block detected on stress electrocardiogram, which developed 1 month after initiation of lopinavir/ritonavir. These two cases highlight the importance of considering lopinavir/ritonavir induced arrhythmias when dealing with HIV-positive individuals.

Details

Title: Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection
Authors/Creators: S.K. Chaubey (Author/Creator) - Cairns Hospital
A.K. Sinha (Author/Creator) - Cairns Hospital
E. Phillips (Author/Creator) - Royal Perth Hospital
D.B. Russell (Author/Creator) - The University of Melbourne
H. Falhammar (Author/Creator) - Karolinska Institutet
Publication Details: Sexual Health, Vol.6(3), pp.254-257
Publisher: CSIRO Publishing
Identifiers: 991005544199107891
Copyright: 2009 CSIRO
Murdoch Affiliation: Institute for Immunology and Infectious Diseases
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.94 Cardiac Arrhythmia; 1.94.470 Cardiac Electrophysiology
Web Of Science research areas: Infectious Diseases; Public, Environmental & Occupational Health
ESI research areas: Clinical Medicine