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Treatment of cryptorchidism with pulsatile luteinizing hormone- releasing hormone (LH-RH)
Journal article   Peer reviewed

Treatment of cryptorchidism with pulsatile luteinizing hormone- releasing hormone (LH-RH)

E.J. Keogh, A. MacKellar, S.A. Mallal, A.G. Dunn, S.C. McColm, C.P. Somerville and C. Glatthaar
Journal of Pediatric Surgery, Vol.18(3), pp.282-283
1983
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Abstract

This preliminary report describes a new method of treating bilateral cryptorchidism that may modify the need for surgical intervention. Four of five boys (3 1/2, 3 1/2, 7, 11 and 12 1/2 years of age) given hourly subcutaneous pulses of luteinizing hormone-releasing hormone (LH-RH, 10 to 100 micrograms/day, given in a 3-min pulse every hour) showed evidence of testicular descent after 3 to 19 weeks. The battery- operated, programmable syringe driver was well tolerated by the boys, and the daily insertion of the scalp-vein needles was managed at home by their parents.

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