Journal article
Trifluoroacetylation of Oxygenated Naphthalenes. Synthesis of some Naphtho[2,3 c]pyran 5,10 quinones
South African Journal of Chemistry, Vol.39(1), pp.46-50
1986
Abstract
Trifluoroacetic anhydride is shown to acylate 1,4,5-tri- and 1.4.5.7-tetramethoxynaphthalene, the former at C(3) or C(8), and the latter at C(8) exclusively. The same reagent also acylates 1-napththol and its 4,8-dialkoxy- and 4,6,8-triatkoxyderivatives to give ortto-trifluoroacetylnaphthols tn good yield. Cerium(IV) ammonium nitrate oxidation of the alkoxynaphthols gives the corresponding 2(1,1-dihydroxy-2- trifluoroethyl)-1 Anaphthoquinones. These quinones undergo hydroxypentylation of the quinonoid nucleus with 3- hydroxyhexanoic acid to give naphthol[2,3-c]pyran-5,10- quinones.
Details
- Title
- Trifluoroacetylation of Oxygenated Naphthalenes. Synthesis of some Naphtho[2,3 c]pyran 5,10 quinones
- Authors/Creators
- R.G.F. Giles (Author/Creator)I.R. Green (Author/Creator)M.L. Niven (Author/Creator)S.C. Yorke (Author/Creator)V.I. Hugo (Author/Creator)
- Publication Details
- South African Journal of Chemistry, Vol.39(1), pp.46-50
- Publisher
- South African Bureau for Scientific Publications
- Identifiers
- 991005541234007891
- Copyright
- © 1986 South African Chemical Institute (SACI)
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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