Triple threats: Tracking antigen-specific T cells in a case of concurrent autoimmunity, infectious disease and possible malignancy

G. Thompson; M. John; A. Chopra

doi:10.1016/j.pathol.2015.12.108

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Triple threats: Tracking antigen-specific T cells in a case of concurrent autoimmunity, infectious disease and possible malignancy

Journal article

Peer reviewed

Triple threats: Tracking antigen-specific T cells in a case of concurrent autoimmunity, infectious disease and possible malignancy

G. Thompson, M. John and A. Chopra

Pathology, Vol.48(Supp. 1), S44

2016

DOI: https://doi.org/10.1016/j.pathol.2015.12.108

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Abstract

We present a case of a 50-year-old man who presented with newly diagnosed HIV infection and a progressive jejunal/omental infiltration causing subacute ileus. He had been diagnosed with celiac disease one year previously. He had a prominent CD8 T cell lymphocytosis demonstrated in peripheral blood, omentum, bone marrow and lymph node biopsies demonstrated two clonal T cell receptor (TCR) gene rearrangements on capillary electrophoresis. Extensive investigations for HIV associated infections were negative.

Details

Title: Triple threats: Tracking antigen-specific T cells in a case of concurrent autoimmunity, infectious disease and possible malignancy
Authors/Creators: G. Thompson (Author/Creator)
M. John (Author/Creator)
A. Chopra (Author/Creator)
Publication Details: Pathology, Vol.48(Supp. 1), S44
Publisher: Elsevier B.V.
Identifiers: 991005544480907891
Murdoch Affiliation: Institute for Immunology and Infectious Diseases
Language: English
Resource Type: Journal article

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