Journal article
Ulceration and stricture of the right dorsal colon after phenylbutazone administration in four horses
Australian Veterinary Journal, Vol.77(12), pp.785-788
1999
Abstract
Four cases of ulceration and stricture of the right dorsal colon were encountered. Ulceration of the right dorsal colon is generally associated with nonsteroidal anti-inflammatory drug (NSAID) toxicosis but there are few reports of stricture following ulceration. All four horses had recent phenylbutazone use: three had been given doses well in excess of the recommended dose and in one the dose was marginally above those recommended but was combined with administration of other NSAIDs. All four horses presented with intermittent low-grade colic, weight loss and ventral oedema. Diarrhoea was also seen in three of them. All had hypoproteinaemia due to severe hypoalbuminaemia, and hyperfibrinogenaemia. Hypoalbuminaemia was less severe in one horse and this horse was successfully managed medically. Two cases were definitively diagnosed at exploratory celiotomy and two at necropsy. Exploratory celiotomy was performed in two horses: one was euthanased at surgery and one was managed successfully with medical treatment and remained normal 1 year after surgery. Medical management included feeding of a low-roughage pelleted ration, corn oil, psyllium mucilloid, and discontinuation of NSAID administration.
Details
- Title
- Ulceration and stricture of the right dorsal colon after phenylbutazone administration in four horses
- Authors/Creators
- M.E. Hough (Author/Creator) - Murdoch UniversityC.M. Steel (Author/Creator) - Murdoch UniversityJ.R. Bolton (Author/Creator) - Murdoch UniversityJ.V. Yovich (Author/Creator) - Murdoch University
- Publication Details
- Australian Veterinary Journal, Vol.77(12), pp.785-788
- Publisher
- Wiley-Blackwell
- Identifiers
- 991005541622907891
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
53 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Citation topics
- 1 Clinical & Life Sciences
- 1.181 Molecular Toxicology
- 1.181.399 NSAIDs and COX Inhibitors
- Web Of Science research areas
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science