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Unifocal langerhans cell histiocytosis presenting as an aggressive bone lesion
Journal article   Peer reviewed

Unifocal langerhans cell histiocytosis presenting as an aggressive bone lesion

K.J. Young and S. George
Journal of Manipulative and Physiological Therapeutics, Vol.28(4), pp.274-277
2005
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Abstract

Objective To discuss a case of unifocal Langerhans cell histiocytosis (eosinophilic granuloma) presenting as an aggressive osseous destructive process. Clinical Features A 6-year-old girl had thigh pain of insidious onset that would wake her at night. Orthopedic testing reproduced local pain, and imaging revealed an osteolytic process in the femoral diaphysis with laminated periosteal reaction. Intervention and Outcome The patient was referred for further evaluation; unifocal Langerhans cell histiocytosis was found at biopsy and spontaneous healing subsequently reported. Conclusions Unifocal Langerhans cell histiocytosis may present with deceptive clinical and imaging findings, of which clinicians should be aware.

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Citation topics
1 Clinical & Life Sciences
1.208 Vasculitis & Autoimmune Disorders
1.208.1682 Langerhans Cell Histiocytosis
Web Of Science research areas
Health Care Sciences & Services
Integrative & Complementary Medicine
Rehabilitation
ESI research areas
Clinical Medicine
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