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Journal article
Validation of three-dimensional thoracic electrical impedance tomography of horses during normal and increased tidal volumes
Physiological measurement, Vol.45, 035010
2024
PMID: 38422515
Abstract
Objective: Data from two-plane electrical impedance tomography (EIT) can be reconstructed into various slices of functional lung images, allowing for more complete visualisation and assessment of lung physiology in health and disease. The aim of this study was to confirm the ability of 3d EIT to visualise normal lung anatomy and physiology at rest and during increased ventilation (represented by rebreathing).
Approach: Two-plane EIT data, using two electrode planes 20cm apart, were collected in 20 standing sedate horses at baseline (resting) conditions, and during rebreathing. EIT data were reconstructed into 3d EIT whereby tidal impedance variation (TIV), ventilated area, and right-left and ventral-dorsal centres of ventilation (CoVRL and CoVVD, respectively) were calculated in cranial, middle and caudal slices of lung, from data collected using the two planes of electrodes.
Main results: There was a significant interaction of time and slice for TIV (p < 0.0001) with TIV increasing during rebreathing in both caudal and middle slices. The ratio of right to left ventilated area was higher in the cranial slice, in comparison to the caudal slice (p = 0.0002). There were significant effects of time and slice on CoVVD whereby the cranial slice was more ventrally distributed than the caudal slice (p < 0.0009 for the interaction).
Significance: The distribution of ventilation in the three slices corresponds with topographical anatomy of the equine lung. This study confirms that 3d EIT can accurately represent lung anatomy and changes in ventilation distribution during rebreathing in standing sedate horses.
Details
- Title
- Validation of three-dimensional thoracic electrical impedance tomography of horses during normal and increased tidal volumes
- Authors/Creators
- David P Byrne - School of Veterinary Medicine, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, AUSTRALIANicole Studer - ITERCristy Secombe - Murdoch University, School of Veterinary MedicineAlexander Cieslewicz - Morrison Critical Care and Pulmonary, 6417 Willow Springs, Morrison, Colorado, 80465, UNITED STATESGiselle Hosgood - Murdoch UniversityAnthea Raisis - Murdoch UniversityAndy Adler - Carleton UniversityMartina Mosing - Anaesthesiology and Perioperative Intensive Care, Department for Companion Animals and Horses, Vetmeduni Vienna, Veterinärplatz 1, Wien, 1210, AUSTRIA
- Publication Details
- Physiological measurement, Vol.45, 035010
- Publisher
- Published on behalf of Institute of Physics and Engineering in Medicine by IOP Publishing Ltd
- Identifiers
- 991005642170307891
- Copyright
- © 2024 The Author(s).
- Murdoch Affiliation
- Harry Butler Institute; Centre for Sustainable Aquatic Ecosystems; School of Veterinary Medicine
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 3 Agriculture, Environment & Ecology
- 3.232 Veterinary Sciences
- 3.232.2141 Equine Respiratory Disorders
- Web Of Science research areas
- Biophysics
- Engineering, Biomedical
- Physiology
- ESI research areas
- Biology & Biochemistry