Vancomycin exposure and acute kidney injury outcome: A Snapshot From the CAMERA2 Study

J. Liu; S.Y.C. Tong; J.S. Davis; N.J. Rhodes; M.H. Scheetz; N. Anagostou; D. Andresen; S. Archuleta; N. Bak; A. Cass; M. Chatfield; A. Cheng; J. Davies; J. Davis; Y. Dishon; R. Dotel; P. Ferguson; H. Foo; V. Fowler; N. Ghosh; T. Gray; S. Guy; N. Holmes; B. Howden; S. Johnson; S. Kalimuddin; D. Lye; S. McBride; G. McKew; N. Meagher; J. Nelson; M. O’Sullivan; D. Paterson; M. Paul; D. Price; A. Ralph; M. Roberts; O. Robinson; B. Rogers; N. Runnegar; S. Smith; A. Sud; S. Tong; A. Tramontana; S. Van Hal; G. Walls; M. Warner; D. Yahav; B. Young

doi:10.1093/ofid/ofaa538

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Vancomycin exposure and acute kidney injury outcome: A Snapshot From the CAMERA2 Study

Journal article

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Vancomycin exposure and acute kidney injury outcome: A Snapshot From the CAMERA2 Study

J. Liu, S.Y.C. Tong, J.S. Davis, N.J. Rhodes, M.H. Scheetz, N. Anagostou, D. Andresen, S. Archuleta, N. Bak, A. Cass, …

Open Forum Infectious Diseases, Vol.7(12), Art. ofaa538

2020

DOI: https://doi.org/10.1093/ofid/ofaa538

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Abstract

Among patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia from a prospective randomized clinical trial, acute kidney injury (AKI) rates increased with increasing vancomycin exposure, even within the therapeutic range. AKI was independently more common for the (flu)cloxacillin group. Day 2 vancomycin AUC ≥470 mg·h/L was significantly associated with AKI, independent of (flu)cloxacillin receipt.

Details

Title: Vancomycin exposure and acute kidney injury outcome: A Snapshot From the CAMERA2 Study
Authors/Creators: J. Liu (Author/Creator)
S.Y.C. Tong (Author/Creator) - Peter Doherty Institute
J.S. Davis (Author/Creator) - Charles Darwin University
N.J. Rhodes (Author/Creator) - Midwestern University
M.H. Scheetz (Author/Creator) - Midwestern University
N. Anagostou (Author/Creator)
D. Andresen (Author/Creator)
S. Archuleta (Author/Creator)
N. Bak (Author/Creator)
A. Cass (Author/Creator)
M. Chatfield (Author/Creator)
A. Cheng (Author/Creator)
J. Davies (Author/Creator)
J. Davis (Author/Creator) - Charles Darwin University
Y. Dishon (Author/Creator)
R. Dotel (Author/Creator)
P. Ferguson (Author/Creator)
H. Foo (Author/Creator)
V. Fowler (Author/Creator)
N. Ghosh (Author/Creator)
T. Gray (Author/Creator)
S. Guy (Author/Creator)
N. Holmes (Author/Creator)
B. Howden (Author/Creator)
S. Johnson (Author/Creator)
S. Kalimuddin (Author/Creator)
D. Lye (Author/Creator)
S. McBride (Author/Creator)
G. McKew (Author/Creator)
N. Meagher (Author/Creator)
J. Nelson (Author/Creator)
M. O’Sullivan (Author/Creator)
D. Paterson (Author/Creator)
M. Paul (Author/Creator)
D. Price (Author/Creator)
A. Ralph (Author/Creator)
M. Roberts (Author/Creator)
O. Robinson (Author/Creator)
B. Rogers (Author/Creator)
N. Runnegar (Author/Creator)
S. Smith (Author/Creator)
A. Sud (Author/Creator)
S. Tong (Author/Creator)
A. Tramontana (Author/Creator)
S. Van Hal (Author/Creator)
G. Walls (Author/Creator)
M. Warner (Author/Creator)
D. Yahav (Author/Creator)
B. Young (Author/Creator)
Publication Details: Open Forum Infectious Diseases, Vol.7(12), Art. ofaa538
Publisher: Oxford University Press on behalf of the Infectious Diseases Society of America.
Identifiers: 991005541799807891
Copyright: © 2020 The Authors.
Murdoch Affiliation: School of Veterinary and Life Sciences
Language: English
Resource Type: Journal article
Additional Information: Courtesy of the CAMERA2 Study Group

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.23 Antibiotics & Antimicrobials; 1.23.173 MRSA and VRE
Web Of Science research areas: Immunology; Infectious Diseases; Microbiology
ESI research areas: Immunology