Journal article
Variation in protein abundance profiles in the M. semitendinosus of lambs bred from sires selected on the basis of growth and muscling potential
Australian Journal of Agricultural Research, Vol.57(6), pp.671-682
2006
Abstract
Relative abundance of proteins localised in the nuclear-enriched, total cell membrane and cytosolic fractions of the semitendinosus muscle was compared between lambs bred from control (C), high muscling (M), and high growth rate (G) sires. In total, 31 proteins were identified whose abundance was differentially regulated between sire type. Differences in hind-limb muscle development between M lambs and C and G lambs were reflected in levels of proteins that regulate or function in cellular mechanisms of protein and energy metabolism. Despite no apparent difference in hind-limb muscle growth in G lambs compared to C, G lambs exhibited marked differences in proteins involved in regulation and function of energy metabolism. These results detail pathways that can be specifically targeted to enhance muscle accretion and growth in lambs. The development of means to manipulate these cellular mechanisms may yield greater gains in muscle accretion and growth rate than breeding on the basis for genetic capacity alone.
Details
- Title
- Variation in protein abundance profiles in the M. semitendinosus of lambs bred from sires selected on the basis of growth and muscling potential
- Authors/Creators
- M.B. McDonagh (Author/Creator) - Department of Environment, Land, Water and PlanningK.L. Ferguson (Author/Creator) - Australian Centre for Plant Functional GenomicsA. Bacic (Author/Creator) - Australian Centre for Plant Functional GenomicsG.E. Gardner (Author/Creator) - University of New EnglandR.S. Hegarty (Author/Creator) - New South Wales Department of Primary Industries
- Publication Details
- Australian Journal of Agricultural Research, Vol.57(6), pp.671-682
- Publisher
- CSIRO Publishing
- Identifiers
- 991005540625207891
- Copyright
- © CSIRO 2006
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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16 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Citation topics
- 3 Agriculture, Environment & Ecology
- 3.51 Dairy & Animal Sciences
- 3.51.206 Meat Quality
- Web Of Science research areas
- Agriculture, Multidisciplinary
- ESI research areas
- Agricultural Sciences