Clonal cytotoxic CD8 + T cell expansion and HLA-B44 supertype association in bupropion-induced severe cutaneous adverse reactions

Letter/Communication

Open access

Peer reviewed

Eric Alves, Ramesh Ram, Eric M Mukherjee, Rama Gangula, Hajirah N Saeed, Matthew S Krantz, Abha Chopra, Mohammadali Ashraf, Andrew Gibson and Elizabeth J Phillips

Journal of investigative dermatology, In Press

2026

PMID: 42173275

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TCR

single cell

drug allergy

HLA

drug reaction

Title: Clonal cytotoxic CD8 + T cell expansion and HLA-B44 supertype association in bupropion-induced severe cutaneous adverse reactions
Authors/Creators: Eric Alves - Murdoch University
Ramesh Ram - Murdoch University
Eric M Mukherjee - Vanderbilt University Medical Center
Rama Gangula - Vanderbilt University Medical Center
Hajirah N Saeed - Massachusetts Eye and Ear Infirmary
Matthew S Krantz - Vanderbilt University Medical Center
Abha Chopra - Murdoch University
Mohammadali Ashraf - University of Illinois Urbana-Champaign
Andrew Gibson - Murdoch University
Elizabeth J Phillips - Murdoch University, Institute for Immunology and Infectious Diseases
Publication Details: Journal of investigative dermatology, In Press
Publisher: Elsevier Inc. on behalf of Society for Investigative Dermatology
Identifiers: 991005884850607891
Murdoch Affiliation: Research and Innovation Office; Institute for Immunology and Infectious Diseases; Personalised Medicine Centre
Language: English
Resource Type: Letter/Communication

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