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Albanitriles A-G: Antiprotozoal Polyacetylene Nitriles from a Mycale Marine Sponge
Journal article   Peer reviewed

Albanitriles A-G: Antiprotozoal Polyacetylene Nitriles from a Mycale Marine Sponge

Samuele Sala, Jane Fromont, Oliver Gomez, Daniel Vuong, Ernest Lacey and Gavin R Flematti
Journal of natural products (Washington, D.C.), Vol.82(12), pp.3450-3455
2019
PMID: 31833368

Abstract

Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Plant Sciences Science & Technology
Seven new nitrile-bearing polyacetylenes, named albanitriles A G, were isolated from a marine sponge of the Mycale genus (Order: Poecilosclerida, Family: Mycalidae) collected near Albany, Western Australia. Structural elucidation was achieved using a combination of high -resolution mass spectrometry and ultraviolet/ visible, infrared, and nuclear magnetic resonance spectroscopy. The compounds were found to possess moderate activity against Giardia duodenalis when compared to a metronidazole positive control.

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Source: InCites

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Collaboration types
Domestic collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.198 Mycotoxins
3.198.749 Porifera
Web Of Science research areas
Chemistry, Medicinal
Pharmacology & Pharmacy
Plant Sciences
ESI research areas
Pharmacology & Toxicology
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