Journal article
Assessing the activity of antimicrobial peptides against common marine bacteria located in rotifer (Brachionus plicatilis) cultures
Probiotics and Antimicrobial Proteins, Vol.14, pp.620-629
2022
Abstract
Rotifers are used as the first feed for marine fish larvae and are grown in large cultures that have high loads of organic matter and heterotrophic bacteria; these bacteria are passed on to the developing fish larvae and can potentially lead to bacterial infections. A modified minimum inhibitory concentration (MIC) protocol for antimicrobial peptides was used to determine the potency of ten antimicrobial peptides (AMPs) in artificial seawater relevant to a rotifer culture (salinity of 25‰) against common marine pathogens. All of the AMPs had antimicrobial activity against the bacterial isolates when the salt concentration was approximately zero. However, in high salt concentrations, the majority of the AMPs had an MIC value greater than 65 µg mL−1 in artificial seawater (25‰). The only exceptions were 2009 (32.5 µg mL−1) and 3002 (32.5 µg mL−1) against Vibrio rotiferianus and Tenacibaculum discolor, respectively. The selected synthetic AMPs were not effective at reducing the bacterial load in brackish salt concentrations of a typical commercial rotifer culture (25‰).
Details
- Title
- Assessing the activity of antimicrobial peptides against common marine bacteria located in rotifer (Brachionus plicatilis) cultures
- Authors/Creators
- C. Woods (Author/Creator) - Murdoch UniversityL. Woolley (Author/Creator) - Department of Primary Industries and Regional DevelopmentG. Partridge (Author/Creator) - Murdoch UniversityM. Chen (Author/Creator) - Department of Primary Industries and Regional DevelopmentE.F. Haney (Author/Creator) - University of British ColumbiaR.E.W. Hancock (Author/Creator) - University of British ColumbiaN. Buller (Author/Creator) - Department of Primary Industries and Regional DevelopmentA. Currie (Author/Creator) - Murdoch University
- Publication Details
- Probiotics and Antimicrobial Proteins, Vol.14, pp.620-629
- Publisher
- Springer New York LLC
- Identifiers
- 991005544385607891
- Copyright
- © 2022 The Authors.
- Murdoch Affiliation
- College of Science, Health, Engineering and Education; Centre for Molecular Medicine and Innovative Therapeutics
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
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- Citation topics
- 2 Chemistry
- 2.190 Surfactants, Lipid Bilayers & Antimicrobial Peptides
- 2.190.857 Antimicrobial Peptides
- Web Of Science research areas
- Biotechnology & Applied Microbiology
- Microbiology
- ESI research areas
- Microbiology