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Published (Version of Record)CC BY V4.0, Open Access
Journal article
Effect of PolyGlycopleX (PGX) consumption on blood lipid profiles in healthy, Low CVD risk overweight adults
Nutrients, Vol.11(4), 717
2019
Abstract
Raised blood lipid levels are associated with a risk of a cardiovascular disease (CVD). Moderate reductions in several CVD factors such as total, low-density lipoprotein (LDL) cholesterol and non-high-density lipoprotein (non-HDL) cholesterol concentrations may be more effective in reducing overall risk than a major reduction in just one. A blind, randomised controlled trial was conducted with 120 healthy overweight (BMI 25–30) adults aged 25–70 years who were non-smokers, not diabetic and of low risk of cardiovascular disease, as assessed by the Framingham risk equation. Participants consumed 4.5 g PolyGlycopleX (PGX) as softgel capsules (PGXS) or 5 g PGX granules (PGXG) or 5 g rice flour (RF) with meals three times a day for 12 weeks. Total, LDL and non-HDL cholesterol were all significantly reduced (−6%, −5% and −3.5%, respectively) post the PGX granule treatment; however, PGX in softgel capsule form did not affect blood lipid profiles. Daily consumption of PGX granules in overweight low CVD risk adults produced lipid changes indicating a CVD preventative benefit.
Details
- Title
- Effect of PolyGlycopleX (PGX) consumption on blood lipid profiles in healthy, Low CVD risk overweight adults
- Authors/Creators
- V.A. Solah (Author/Creator) - Curtin UniversityD.A. Kerr (Author/Creator) - Curtin UniversityD. Irawati (Author/Creator) - University of MataramW. Hunt (Author/Creator) - Curtin UniversityX. Meng (Author/Creator) - Flinders UniversityR.J. Gahler (Author/Creator) - Factors Group R & D, Burnaby, BC V3N4S9, Canada. rgahler@naturalfactors.com.R.J. Fenton (Author/Creator)H.K. Fenton (Author/Creator) - Curtin UniversityS.K. Johnson (Author/Creator) - Curtin UniversityA.P. James (Author/Creator) - Curtin University
- Publication Details
- Nutrients, Vol.11(4), 717
- Publisher
- MDPI
- Identifiers
- 991005544392007891
- Copyright
- © 2019 by the authors.
- Murdoch Affiliation
- Murdoch University; College of Environmental and Life Sciences
- Language
- English
- Resource Type
- Journal article
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