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Journal article
Exploring the genetic architecture of powdery mildew resistance in wheat through QTL meta-analysis
Frontiers in plant science, Vol.15, 1386494
2024
PMID: 39022610
Abstract
Powdery mildew (PM), caused by Blumeria graminis f. sp. tritici, poses a significant threat to wheat production, necessitating the development of genetically resistant varieties for long-term control. Therefore, exploring genetic architecture of PM in wheat to uncover important genomic regions is an important area of wheat research. In recent years, the utilization of meta-QTL (MQTL) analysis has gained prominence as an essential tool for unraveling the complex genetic architecture underlying complex quantitative traits. The aim of this research was to conduct a QTL meta-analysis to pinpoint the specific genomic regions in wheat responsible for governing PM resistance. This study integrated 222 QTLs from 33 linkage-based studies using a consensus map with 54,672 markers. The analysis revealed 39 MQTLs, refined to 9 high-confidence MQTLs (hcMQTLs) with confidence intervals of 0.49 to 12.94 cM. The MQTLs had an average physical interval of 41.00 Mb, ranging from 0.000048 Mb to 380.71 Mb per MQTL. Importantly, 18 MQTLs co-localized with known resistance genes like Pm2, Pm3, Pm8, Pm21, Pm38, and Pm41. The study identified 256 gene models within hcMQTLs, providing potential targets for marker-assisted breeding and genomic prediction programs to enhance PM resistance. These MQTLs would serve as a foundation for fine mapping, gene isolation, and functional genomics studies, facilitating a deeper understanding of molecular mechanisms. The identification of candidate genes opens up exciting possibilities for the development of PM-resistant wheat varieties after validation.
Details
- Title
- Exploring the genetic architecture of powdery mildew resistance in wheat through QTL meta-analysis
- Authors/Creators
- Divya Sharma - National Bureau of Plant Genetic ResourcesNeeraj Budhlakoti - Indian Agricultural Statistics Research InstituteAnita Kumari - University of DelhiDinesh Kumar Saini - Punjab Agricultural UniversityAnshu Sharma - National Bureau of Plant Genetic ResourcesAakash Yadav - National Bureau of Plant Genetic ResourcesReyazul Rouf Mir - Sher-e-Kashmir University of Agricultural Sciences and Technology of KashmirAmit Kumar Singh - National Bureau of Plant Genetic ResourcesV. K. Vikas - Indian Agricultural Research InstituteGyanendra Pratap Singh - National Bureau of Plant Genetic ResourcesSundeep Kumar - National Bureau of Plant Genetic Resources
- Publication Details
- Frontiers in plant science, Vol.15, 1386494
- Publisher
- Frontiers Media S.A
- Identifiers
- 991005722667307891
- Copyright
- ©2024 Sharma, Budhlakoti, Kumari, Saini, Sharma, Yadav, Mir, Singh, Vikas, Singhand Kumar.
- Murdoch Affiliation
- Food Futures Institute
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 3 Agriculture, Environment & Ecology
- 3.4 Crop Science
- 3.4.96 QTL
- Web Of Science research areas
- Plant Sciences
- ESI research areas
- Plant & Animal Science