Health Related Quality of Life and Sleep Regularity Among Middle-Aged to Older Adults From the Community

Kelly Sansom; Murthy M N Mittinty; Hannah Scott; Bastien Lechat; Daniel Windred; Andrew J K Phillips; Robert Adams; Peter R Eastwood; Amy C Reynolds

doi:10.1111/jsr.70194

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Health Related Quality of Life and Sleep Regularity Among Middle-Aged to Older Adults From the Community

Journal article

Open access

Peer reviewed

Health Related Quality of Life and Sleep Regularity Among Middle-Aged to Older Adults From the Community

Kelly Sansom, Murthy M N Mittinty, Hannah Scott, Bastien Lechat, Daniel Windred, Andrew J K Phillips, Robert Adams, Peter R Eastwood and Amy C Reynolds

Journal of sleep research, e70194

2025

DOI: https://doi.org/10.1111/jsr.70194

PMID: 40903419

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Abstract

sleep patterns

sleep consistency

physical health

irregular sleep

mental health

Irregular sleep is increasingly related to poorer health, with stronger links to cardiovascular disease and mortality than sleep duration. Its impact on health-related quality of life, however, remains unclear, particularly in community-based populations. This study examined whether objectively measured sleep regularity is associated with physical and mental health-related quality of life. Sleep regularity was calculated using the Sleep Regularity Index from actigraphy data in 768 middle-aged to older adults from the Raine Study (median age [range] = 57 [53–61]; 58% female). Physical and mental health-related quality of life were assessed using the 12-item Short Form Health Survey. Quantile regression was used to examine associations at the 25th, 50th, and 75th percentiles, adjusting for age, sex, comorbidity count, sleep duration, and shift work. Median sleep regularity scores declined with self-rated health, from 77.17 (excellent) to 61.49 (poor). A 10-unit increase in sleep regularity was associated with higher mental health scores at the 25th (1.80; 95% CI: 0.90–2.60), 50th (1.20; 95% CI: 0.50–1.90), and 75th (0.50; 95% CI: 0.20–0.90) percentiles. For physical health, a 10-unit increase in sleep regularity was associated with a 1.20 (95% CI: 0.30–2.20) higher score at the 25th percentile, with no evidence of association at higher percentiles. These findings suggest that poorer sleep regularity is related to lower physical and mental health-related quality of life. Future research should explore whether improving sleep regularity can enhance quality of life in middle-aged to older adults.

Details

Title: Health Related Quality of Life and Sleep Regularity Among Middle-Aged to Older Adults From the Community
Authors/Creators: Kelly Sansom - Murdoch University
Murthy M N Mittinty - Flinders University
Hannah Scott - Flinders University
Bastien Lechat - Adelaide Institute for Sleep Health
Daniel Windred - Adelaide Institute for Sleep Health
Andrew J K Phillips - Adelaide Institute for Sleep Health
Robert Adams - Adelaide Institute for Sleep Health
Peter R Eastwood - Murdoch University
Amy C Reynolds - Adelaide Institute for Sleep Health
Publication Details: Journal of sleep research, e70194
Publisher: WILEY
Number of pages: 9
Grant note: National Health and Medical Research Council
Identifiers: 991005811025407891
Murdoch Affiliation: Centre for Healthy Ageing; Vice Chancellery
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.137 Sleep Science & Circadian Systems; 1.137.349 Insomnia
Web Of Science research areas: Clinical Neurology; Neurosciences
ESI research areas: Neuroscience & Behavior