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Journal article
Health Related Quality of Life and Sleep Regularity Among Middle-Aged to Older Adults From the Community
Journal of sleep research, e70194
2025
PMID: 40903419
Abstract
Irregular sleep is increasingly related to poorer health, with stronger links to cardiovascular disease and mortality than sleep duration. Its impact on health-related quality of life, however, remains unclear, particularly in community-based populations. This study examined whether objectively measured sleep regularity is associated with physical and mental health-related quality of life. Sleep regularity was calculated using the Sleep Regularity Index from actigraphy data in 768 middle-aged to older adults from the Raine Study (median age [range] = 57 [53–61]; 58% female). Physical and mental health-related quality of life were assessed using the 12-item Short Form Health Survey. Quantile regression was used to examine associations at the 25th, 50th, and 75th percentiles, adjusting for age, sex, comorbidity count, sleep duration, and shift work. Median sleep regularity scores declined with self-rated health, from 77.17 (excellent) to 61.49 (poor). A 10-unit increase in sleep regularity was associated with higher mental health scores at the 25th (1.80; 95% CI: 0.90–2.60), 50th (1.20; 95% CI: 0.50–1.90), and 75th (0.50; 95% CI: 0.20–0.90) percentiles. For physical health, a 10-unit increase in sleep regularity was associated with a 1.20 (95% CI: 0.30–2.20) higher score at the 25th percentile, with no evidence of association at higher percentiles. These findings suggest that poorer sleep regularity is related to lower physical and mental health-related quality of life. Future research should explore whether improving sleep regularity can enhance quality of life in middle-aged to older adults.
Details
- Title
- Health Related Quality of Life and Sleep Regularity Among Middle-Aged to Older Adults From the Community
- Authors/Creators
- Kelly Sansom - Murdoch University, Centre for Healthy AgeingMurthy M.N. Mittinty - Flinders UniversityHannah Scott - Flinders UniversityBastien Lechat - Adelaide Institute for Sleep HealthDaniel Windred - Monash UniversityAndrew J.K. Phillips - Adelaide Institute for Sleep HealthRobert Adams - Adelaide Institute for Sleep HealthPeter R. Eastwood - Murdoch University, Vice ChancelleryAmy C. Reynolds - Flinders University
- Publication Details
- Journal of sleep research, e70194
- Publisher
- John Wiley & Sons Ltd on behalf of European Sleep Research Society.
- Number of pages
- 9
- Grant note
- National Health and Medical Research Council (http://data.elsevier.com/vocabulary/SciValFunders/501100000925) University of Notre Dame Australia University of Western Australia NHMRC Telethon Kids Institute, Women and Infants Research Foundation Raine Medical Research Foundation Curtin University
- Identifiers
- 991005812249407891
- Copyright
- © 2025 The Author(s).
- Murdoch Affiliation
- Centre for Healthy Ageing; Vice Chancellery
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.137 Sleep Science & Circadian Systems
- 1.137.349 Insomnia
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
- ESI research areas
- Neuroscience & Behavior