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Improvements in symptoms and quality of life following exercise training in older adults with moderate/severe persistent asthma
Journal article   Peer reviewed

Improvements in symptoms and quality of life following exercise training in older adults with moderate/severe persistent asthma

Sian Turner, Peter Eastwood, Angus Cook and Sue Jenkins
Respiration, Vol.81(4), pp.302-310
2011
PMID: 20501982
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Published (Version of Record)

Abstract

Asthma Exercise training Rehabilitation Quality of life Exercise tests
Background: Some individuals with moderate/severe persistent asthma develop irreversible airway obstruction. These individuals present with dyspnoea, exercise intolerance and impaired quality of life (QOL), all of which could potentially be alleviated with exercise training. Objective: To investigate whether exercise training improves functional exercise capacity and QOL in middle-aged and older adults with fixed airway obstruction asthma (FAOA). Methods: 35 subjects aged 67.8 ± 10.6 years, with FEV1 59 ± 16% of predicted, were randomised to a 6-week ‘intervention’ period of supervised exercise training (n = 20) or usual care (n = 15). This period was preceded by a 3-week run-in period during which asthma control was assessed weekly. Functional exercise capacity (6-min walk distance, 6MWD) and QOL (Asthma QOL Questionnaire, AQLQ) were measured before, immediately following and 3 months after the intervention period. Results: 34 subjects (exercise group, n = 19, and control group, n = 15) completed the intervention period. Relative to the control group, the exercise group had greater improvements immediately following and 3 months after the intervention in the AQLQ symptom domain (0.61, p = 0.001, and 0.57 points per item, p = 0.005) and AQLQ activity limitation domain (0.43, p = 0.04, and 0.55 points per item, p = 0.04). 6MWD increased (36 ± 37 m, p < 0.01) in the exercise group immediately following training and remained elevated (34 ± 45 m, p < 0.01) at the 3-month follow-up. The magnitude of change in 6MWD between groups was not significant, despite no change in the control group. Conclusions: Supervised exercise training improves symptoms and QOL in adults with FAOA.

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.65 Allergy
1.65.44 Asthma
Web Of Science research areas
Respiratory System
ESI research areas
Clinical Medicine
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