Journal article
Managing obstruction of the central airways
Internal medicine journal, Vol.40(6), pp.399-410
2010
PMID: 19849741
Abstract
Lung cancer is the most common cause of cancer death in Australia, Europe and the USA. Up to 20–30% of these cancers eventually affect the central airways and result in reduced quality of life, dyspnoea, haemoptysis, post-obstructive pneumonia and ultimately death. Non-malignant processes may also lead to central airway obstruction and can have similar symptoms. With the development of newer technologies, the last 20 years have seen the emergence of the field of interventional pulmonology to deal specifically with the diagnosis and management of thoracic malignancy, including obstruction of the central airways. This review discusses the pathology, pre-procedure work-up and management options for obstructing central airway lesions. Several treatment modalities exist for dealing with endobronchial pathology with local availability and expertise guiding choice of treatment. While the literature lacks large, multicentre, randomized studies defining the optimal management strategy for a given problem, there is growing evidence from numerous case studies of improved physiology, of quality of life and possibly of survival with modern interventional techniques.
Details
- Title
- Managing obstruction of the central airways
- Authors/Creators
- J. P. Williamson - Sir Charles Gairdner Hosp, Dept Pulm Physiol, Perth, WA, AustraliaM. J. Phillips - College Station Medical CenterD. R. Hillman - Sir Charles Gairdner Hosp, Dept Pulm Physiol, Perth, WA, AustraliaP. R. Eastwood - Sir Charles Gairdner Hosp, Dept Pulm Physiol, Perth, WA, Australia
- Publication Details
- Internal medicine journal, Vol.40(6), pp.399-410
- Publisher
- Wiley
- Number of pages
- 12
- Grant note
- 513854; 463926; 513704 / Australian National Health and Medical Research Council (NHMRC); National Health and Medical Research Council (NHMRC) of Australia Sir Charles Gairdner Hospital University of Western Australia
- Identifiers
- 991005592657507891
- Copyright
- © 2010 The Authors
- Murdoch Affiliation
- Vice Chancellery
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.235 Throat & Voice Disorders
- 1.235.1127 Tracheal Obstructions
- Web Of Science research areas
- Respiratory System
- ESI research areas
- Clinical Medicine