Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions

Peter R. Eastwood; Atul Malhotra; Lyle J. Palmer; Eric J. Kezirian; Richard L. Horner; Mary S. Ip; Robert Thurnheer; Nick A. Antic; David R. Hillman

doi:10.1111/j.1440-1843.2009.01699.x

Back

Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions

Journal article

Peer reviewed

Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions

Peter R. Eastwood, Atul Malhotra, Lyle J. Palmer, Eric J. Kezirian, Richard L. Horner, Mary S. Ip, Robert Thurnheer, Nick A. Antic and David R. Hillman

Respirology (Carlton, Vic.), Vol.15(4), pp.587-595

2010

DOI: https://doi.org/10.1111/j.1440-1843.2009.01699.x

PMCID: PMC4342116

PMID: 20136736

Files and links (1)

url

PublishedView

Published (Version of Record)

Abstract

pathogenesis

sleep apnoea syndrome

treatment

Obstructive sleep apnoea (OSA) is a common disease, recognized as an independent risk factor for a range of clinical conditions, such as hypertension, stroke, depression and diabetes. Despite extensive research over the past two decades, the mechanistic links between OSA and other associated clinical conditions, including metabolic disorders and cardiovascular disease, remain unclear. Indeed, the pathogenesis of OSA itself remains incompletely understood. This review provides opinions from a number of leading experts on issues related to OSA and its pathogenesis, interaction with anaesthesia, metabolic consequences and comorbidities, cardiovascular disease, genetics, measurement and diagnosis, surgical treatment and pharmacotherapeutic targets.

Details

Title: Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions
Authors/Creators: Peter R. Eastwood - West Australian Sleep Disorders Research Institute
Atul Malhotra - Brigham and Women's Hospital
Lyle J. Palmer - The University of Western Australia
Eric J. Kezirian - University of California, San Francisco
Richard L. Horner - University of Toronto
Mary S. Ip - Queen Mary Hospital
Robert Thurnheer - Kantonsspital Münsterlingen
Nick A. Antic - Adelaide Institute for Sleep Health
David R. Hillman - Sir Charles Gairdner Hospital
Publication Details: Respirology (Carlton, Vic.), Vol.15(4), pp.587-595
Identifiers: 991005592647407891
Copyright: © 2010 The Authors
Murdoch Affiliation: Vice Chancellery
Language: English
Resource Type: Journal article

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Metrics

44 Record Views

73 Times Cited - Web of Science

See more details

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.137 Sleep Science & Circadian Systems; 1.137.382 Obstructive Sleep Apnea
Web Of Science research areas: Respiratory System
ESI research areas: Clinical Medicine