Routine Emollient Therapy with Coconut Oil in Preterm Infants and Allergic Sensitization at 1-Year Corrected Age

Terri Williams; Jemma Weidinger; Jessica R. Metcalfe; Samantha Thomas; Jenny Mountain; Andrew Currie; Michael O'Sullivan; Tobias Strunk

doi:10.1159/000546309

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Routine Emollient Therapy with Coconut Oil in Preterm Infants and Allergic Sensitization at 1-Year Corrected Age

Journal article

Open access

Peer reviewed

Routine Emollient Therapy with Coconut Oil in Preterm Infants and Allergic Sensitization at 1-Year Corrected Age

Terri Williams, Jemma Weidinger, Jessica R. Metcalfe, Samantha Thomas, Jenny Mountain, Andrew Currie, Michael O'Sullivan and Tobias Strunk

Neonatology (Basel, Switzerland)

2025

DOI: https://doi.org/10.1159/000546309

PMID: 40472816

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Abstract

Life Sciences & Biomedicine

Pediatrics

Science & Technology

Introduction: Skin care for very and extremely preterm infant is an important and previously underappreciated topic. Coconut oil skin care for preterm infants is a promising option, but several important questions remain including the theoretical potential for allergic sensitization. Methods: This prospective study conducted skin prick testing and allergy questionnaires in a cohort of very preterm infants who received routine skin care with virgin coconut oil during their neonatal admission. Results: Ninety infants (median GA 28.2 weeks, median BW 1,048 g) were assessed at corrected age 15 months. A total of 8 children had positive skin prick tests to 1 or more of the most common allergens (egg, peanut, cashew, dust mite). No child was sensitized to coconut oil or extract. Conclusions: We did not find evidence of allergic sensitization following neonatal skin care with coconut oil in children born preterm.

Details

Title: Routine Emollient Therapy with Coconut Oil in Preterm Infants and Allergic Sensitization at 1-Year Corrected Age
Authors/Creators: Terri Williams - Perth Childrens Hosp, Immunol Dept, Perth, WA, Australia
Jemma Weidinger - Perth Childrens Hosp, Immunol Dept, Perth, WA, Australia
Jessica R. Metcalfe - Perth Childrens Hosp, Immunol Dept, Perth, WA, Australia
Samantha Thomas - Perth Childrens Hosp, Immunol Dept, Perth, WA, Australia
Jenny Mountain - Mécanique et Engrenage Moderne (France)
Andrew Currie - Murdoch University, Personalised Medicine Centre
Michael O'Sullivan - Perth Childrens Hosp, Immunol Dept, Perth, WA, Australia
Tobias Strunk - King Edward Mem Hosp Women, Neonatal Directorate, Perth, WA, Australia
Publication Details: Neonatology (Basel, Switzerland)
Publisher: S. Karger AG, Basel
Number of pages: 4
Grant note: Neonatal Directorate Northern Star Resources community grant Departmentof Allergy and Immunology
Identifiers: 991005794757207891
Murdoch Affiliation: School of Medical, Molecular and Forensic Sciences; Personalised Medicine Centre
Language: English
Resource Type: Journal article

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Collaboration types: Industry collaboration; Domestic collaboration
Citation topics: 2 Chemistry; 2.176 Drug Delivery Chemistry; 2.176.771 Transdermal Delivery
Web Of Science research areas: Pediatrics
ESI research areas: Clinical Medicine